Gastrointestinal
1) Choose either oral or intravenous route for treatment
2) For oral treatment, administer sublingual Ondansetron 2 - 4 mg ODT (orally dissolving tablet).
a) Cut one 4 mg ODT in 1/2 for the 2 mg <20 kg
b) Give the whole 4 mg tablet for > 20 kg
c) Repeat once if needed after 5 minutes.
d) For a semi-cooperative child, sublingual/tucked in the cheek/anywhere in the mouth/swallowed it accidentally are all acceptable
3) For intravenous treatment, establish IV Normal Saline at TKO rate, administer Ondansetron IV dose = 0.1 mg / kg, max 4 mg to be given slowly over 2 minutes, with IV fluids running
4) If vomiting is not controlled after 5 minutes, you may repeat the initial IV dose once
5) Apply pulse oximeter and evaluate the patient for possible serious causes of vomiting