FENTANYL CITRATE (SUBLIMAZE)

CLASS:

• Narcotic (Opioid) Analgesic (Schedule II)

ACTION:

• CNS Depressant, Binds to opiate receptors producing analgesia and euphoria

• Reduces the brainstem respiratory centers responsiveness to CO2, also depresses pontine and medullary centers involved in regulating respiratory rhythmicity thus produces respiratory depression.

INDICATION:

• pain control

• maintenance of analgesia and adjunct to RSI

CONTRAINDICATION:

• Hypersensitivity

• Respiratory Depression

• Myasthenia gravis

STANDARD PREP:

• 50 mcg/ml

  (80-100 times as potent as Morphine Sulfate)

DOSAGE/ROUTE:

• 50 – 100 mcg/dose (0.05 – 0.1 mg) IM or IV/IO

  (slow 1-2 min) max. dose 150 mcg (0.15 mg)

• Onset: Immediate — Peak: 3-5 min (IV) — Duration: 30-60 min

PEDS DOSE:

• 1 – 2 mcg/kg IM or IV/IO (slow 1-2 min) [Need to contact BSP]

SIDE EFFECTS:

• Respiratory depression

• Hypotension

• Dysrhythmias

• Palpitations

• CNS depression or euphoria

• Dizziness

• N/V

PRECAUTION:

• Use with caution in patients with traumatic brain injury

• Serious respiratory depression can be reversed with naloxone (Narcan) if necessary.